diff --git a/virtual-patient-model/src/main/java/com/supervision/vo/ask/ModifyPrimaryDiseaseInfoReqVO.java b/virtual-patient-model/src/main/java/com/supervision/vo/ask/ModifyPrimaryDiseaseInfoReqVO.java
index 4b22d353..04f82450 100644
--- a/virtual-patient-model/src/main/java/com/supervision/vo/ask/ModifyPrimaryDiseaseInfoReqVO.java
+++ b/virtual-patient-model/src/main/java/com/supervision/vo/ask/ModifyPrimaryDiseaseInfoReqVO.java
@@ -2,9 +2,12 @@ package com.supervision.vo.ask;
 
 import lombok.Data;
 
+import javax.validation.constraints.NotBlank;
+
 @Data
 public class ModifyPrimaryDiseaseInfoReqVO {
 
+    @NotBlank(message = "初步诊断ID不能为空")
     private String id;
 
     private String patientDiseaseInfo;
diff --git a/virtual-patient-web/src/main/java/com/supervision/controller/AskPrimaryController.java b/virtual-patient-web/src/main/java/com/supervision/controller/AskPrimaryController.java
index ba25f10a..290d228d 100644
--- a/virtual-patient-web/src/main/java/com/supervision/controller/AskPrimaryController.java
+++ b/virtual-patient-web/src/main/java/com/supervision/controller/AskPrimaryController.java
@@ -16,12 +16,15 @@ import io.swagger.annotations.ApiModelProperty;
 import io.swagger.annotations.ApiOperation;
 import io.swagger.annotations.ApiParam;
 import lombok.RequiredArgsConstructor;
+import org.springframework.validation.annotation.Validated;
 import org.springframework.web.bind.annotation.*;
 
+import javax.validation.Valid;
 import javax.validation.constraints.NotBlank;
 import java.util.List;
 
 @Api(tags = "初步诊断")
+@Validated
 @RestController
 @RequestMapping("askPrimary")
 @RequiredArgsConstructor
@@ -31,7 +34,7 @@ public class AskPrimaryController {
 
     @ApiOperation("查询初步诊断列表")
     @GetMapping("queryAskPrimaryList")
-    public List<DiagnosisPrimaryVO> queryAskPrimaryList(String processId) {
+    public List<DiagnosisPrimaryVO> queryAskPrimaryList(@NotBlank(message = "流程ID不能为空") String processId) {
         return askPrimaryService.queryAskPrimaryList(processId);
     }
 
@@ -43,13 +46,13 @@ public class AskPrimaryController {
 
     @ApiOperation("修改初步诊断病情依据")
     @PostMapping("modifyPrimaryDiseaseInfo")
-    public void modifyPrimaryDiseaseInfo(@RequestBody ModifyPrimaryDiseaseInfoReqVO reqVO) {
+    public void modifyPrimaryDiseaseInfo(@RequestBody @Validated ModifyPrimaryDiseaseInfoReqVO reqVO) {
         askPrimaryService.modifyPrimaryDiseaseInfo(reqVO);
     }
 
     @ApiOperation("新增初步诊断")
     @PostMapping("savePrimary")
-    public void savePrimary(@RequestBody SaveDiagnosisPrimaryReqVO reqVO) {
+    public void savePrimary(@RequestBody @Validated SaveDiagnosisPrimaryReqVO reqVO) {
         askPrimaryService.savePrimary(reqVO);
     }
 
@@ -61,7 +64,7 @@ public class AskPrimaryController {
 
     @ApiOperation("删除初步诊断")
     @GetMapping("deletePrimary")
-    public void deletePrimary(String id) {
+    public void deletePrimary(@NotBlank(message = "初步诊断ID不能为空") String id) {
         askPrimaryService.deletePrimary(id);
     }
 
@@ -74,7 +77,7 @@ public class AskPrimaryController {
 
     @ApiOperation("确认诊断页面,保存初步诊断以及鉴别依据")
     @PostMapping("confirmPrimaryByAskEnd")
-    public void confirmPrimaryByAskEnd(@RequestBody List<PrimaryConfirmReqVO> reqVOList) {
+    public void confirmPrimaryByAskEnd(@RequestBody @Valid List<PrimaryConfirmReqVO> reqVOList) {
         askPrimaryService.confirmPrimaryByAskEnd(reqVOList);
     }
 }
diff --git a/virtual-patient-web/src/main/java/com/supervision/pojo/vo/PrimaryConfirmReqVO.java b/virtual-patient-web/src/main/java/com/supervision/pojo/vo/PrimaryConfirmReqVO.java
index e8a20e37..aa32e468 100644
--- a/virtual-patient-web/src/main/java/com/supervision/pojo/vo/PrimaryConfirmReqVO.java
+++ b/virtual-patient-web/src/main/java/com/supervision/pojo/vo/PrimaryConfirmReqVO.java
@@ -3,14 +3,17 @@ package com.supervision.pojo.vo;
 import io.swagger.annotations.ApiModelProperty;
 import lombok.Data;
 
+import javax.validation.constraints.NotBlank;
 import java.util.List;
 
 @Data
 public class PrimaryConfirmReqVO {
 
     @ApiModelProperty("初步诊断ID")
+    @NotBlank(message = "初步诊断ID不能为空")
     private String primaryId;
 
+    @NotBlank(message = "流程ID不能为空")
     private String processId;
 
 
diff --git a/virtual-patient-web/src/main/java/com/supervision/pojo/vo/SaveDiagnosisPrimaryReqVO.java b/virtual-patient-web/src/main/java/com/supervision/pojo/vo/SaveDiagnosisPrimaryReqVO.java
index bc907fd0..63ee0dff 100644
--- a/virtual-patient-web/src/main/java/com/supervision/pojo/vo/SaveDiagnosisPrimaryReqVO.java
+++ b/virtual-patient-web/src/main/java/com/supervision/pojo/vo/SaveDiagnosisPrimaryReqVO.java
@@ -9,6 +9,7 @@ import io.swagger.annotations.ApiModelProperty;
 import lombok.Data;
 import lombok.EqualsAndHashCode;
 
+import javax.validation.constraints.NotBlank;
 import java.util.List;
 
 @Data
@@ -19,12 +20,14 @@ public class SaveDiagnosisPrimaryReqVO  {
      * 诊断流程ID
      */
     @ApiModelProperty("诊断流程ID")
+    @NotBlank(message = "诊断流程ID不能为空")
     private String processId;
 
     /**
      * 初步诊断疾病,关联disease表ID
      */
     @ApiModelProperty("初步诊断疾病ID,关联disease表ID")
+    @NotBlank(message = "初步诊断疾病ID不能为空")
     private String primaryDiagnosisId;
 
     @ApiModelProperty("患者病情(初步诊断填写)")